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Selank

01 Summary

A synthetic peptide developed in Russia from tuftsin, an immune peptide. It is used to take the edge off anxiety and stress while keeping you clear-headed.

02 How it works

Selank appears to work on the GABA system — the brain’s main calming pathway — in a gentler way than sedative drugs, and to slow the breakdown of enkephalins, the body’s own calming messengers. In studies it reduced anxiety without sedation or memory effects.

03 Common uses

Stress and anxietyCalm focusSleep that is disrupted by a busy mind

04 Run profile

A gentle first week, then a steady amount. Two or three times a week, in the morning rather than late, in twelve-week blocks.

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05 Pairs well with

06 What to watch for

Headache and injection-site tenderness; mild nausea or sinus irritation as a spray. Unexpected sedation or mood change is worth flagging. Unlike benzodiazepines, no sedation, dependence or withdrawal has been reported.

07 Evidence & status

Not FDA-approved

Small clinical studies in Russia and animal research; little Western trial data.

Approved as a medicine in Russia; not FDA-approved.

08 FAQ

Will it make me drowsy?

It is not known for sedation — people describe calm, not sleepy.

Can I take it with Semax?

Yes, they are commonly paired: Semax for focus, Selank for calm.

Is it habit-forming?

No dependence or withdrawal has been reported.

Educational information only — not medical advice. The Daily Stack does not sell or supply any products. Talk to a licensed healthcare professional about your own health decisions.